Gene Mutation May Explain Heart Disease Risk Among African-Americans
MONDAY, Dec. 2, 2013 (HealthDay News) -- A genetic mutation associated with an increased risk of heart disease, type 2 diabetes and other health problems is common in Africans and people of African descent worldwide, according to a new study.
The findings may help explain why Africans and people of African descent are more likely to develop heart disease and diabetes than many other racial groups, the Weill Cornell Medical College researchers said.
The mutation in the ApoE gene is linked to increased levels of triglycerides, which are fats in the blood associated with conditions such as obesity, diabetes, stroke and heart disease.
The researchers' analysis of worldwide data revealed that the "R145C" variant of the ApoE gene is found in 5 percent to 12 percent of Africans and people of African descent, especially those from sub-Saharan Africa. The variant is rare in people who are not African or of African descent.Read entire article...