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Brain Chemicals May Signal Which Preemies Will Have Delays

TUESDAY, Dec. 17, 2013 (HealthDay News) -- A potential new way to identify premature infants at high risk for delays in motor skills development may have been discovered by researchers.

The researchers conducted brain scans on 43 infants in the United Kingdom who were born at less than 32 weeks' gestation and admitted to a neonatal intensive care unit (NICU). The scans focused on the brain's white matter, which is especially fragile in newborns and at risk for injury. They also conducted tests that measured certain brain chemical levels.

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HealthCare News

Gene Mutation Links Sporadic and Inherited ALS Cases

FRIDAY, May 7 (HealthDay News) -- A newly found genetic link between most cases of amyotrophic lateral sclerosis, also known as ALS or Lou Gehrig's disease, potentially opens the door to new treatments, researchers say.

In the majority of cases, ALS occurs randomly from an unknown cause, but about 5% to 10% of cases are genetic and run in families. About 30% of those familial cases have been linked to specific genetic mutations.

In the new study, released online April 14 in advance of publication in an upcoming print issue of the Annals of Neurology, researchers analyzed the spinal cords and brains of 100 people who had died, 78 of whom had ALS. The investigators found one kind of genetic mutation in almost all of the cases.

"This is a game changer because it establishes a connection in the development of sporadic ALS with a known cause of familial ALS," senior author Dr. Teepu Siddique, a professor in the Davee Department of Neurology and Clinical Neurosciences at Northwestern University Feinberg School of Medicine in Chicago, said in a news release. "Our finding opens up a new field of investigation for rational therapy for all of ALS. This is the holy grail of researchers in this field."

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